SHANK2 抗体 (PDZ Domain, SH3 Domain)
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- 抗原 See all SHANK2 抗体
- SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))
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抗原表位
- AA 84-309, PDZ Domain, SH3 Domain
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SHANK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Detects ~160 kDa protein. This antibody recognizes Shank1, Shank2 and Shank3.
- 产品特性
- Synonyms: Shank1, Shank2, Shank3, SPANK-3, ProSAP1, ProSAP2, Cortbp1, SSTRIP, KIAA1650, PSAP2,SH3 and multiple ankyrin repeat domains protein
- 纯化方法
- Protein G Chromatography.
- 免疫原
- Fusion protein amino acids 84-309 (SH3/PDZ domains) of Rat Shank2 (accession numberQ9QX74).
- 克隆位点
- S23b-49
- 亚型
- IgG1
- Top Product
- Discover our top product SHANK2 Primary Antibody
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anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody
SHANK2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) unconjugated
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (FITC)SHANK2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N23b-6 (Formerly S23b-6) FITC
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Alkaline Phosphatase (AP))SHANK2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N23b-6 (Formerly S23b-6) Alkaline Phosphatase (AP)
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Biotin)SHANK2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N23b-6 (Formerly S23b-6) Biotin
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (APC)SHANK2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N23b-6 (Formerly S23b-6) APC
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 488)SHANK2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N23b-6 (Formerly S23b-6) Atto 488
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 594)SHANK2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N23b-6 (Formerly S23b-6) Atto 594
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 390)SHANK2 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N23b-6 (Formerly S23b-6) Atto 390
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 728-822) antibodySHANK2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 1042-1475) antibodySHANK2 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1 μg/mL1 μg/mL was sufficient for detection of Shank1-4 in 10 μg of rat brain lysate by colorimetricimmunoblot analysis using Goat anti-mouse IgG: HRP as the secondary antibody. Immunoprecipitation: 1.0-10 μg/mLImmunofluorescence: 1.0-10 μg/mLImmunocytochemistry: 0.1-1.0 μg/mLImmunohistochemistry: 0.1-1.0 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.4 containing 50 % Glycerol as stabilizer and 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))
- 别名
- SHANK2 (SHANK2 产品)
- 别名
- AUTS17 antibody, CORTBP1 antibody, CTTNBP1 antibody, ProSAP1 antibody, SHANK antibody, SPANK-3 antibody, mKIAA1022 antibody, auts17 antibody, cortbp1 antibody, cttnbp1 antibody, prosap1 antibody, spank-3 antibody, shank2 antibody, MGC122482 antibody, CortBP1 antibody, Spank-3 antibody, SHANK2 antibody, SH3 and multiple ankyrin repeat domains 2 antibody, SH3 and multiple ankyrin repeat domains 2 L homeolog antibody, SH3 and multiple ankyrin repeat domains protein 2 antibody, SHANK2 antibody, Shank2 antibody, shank2.L antibody, shank2 antibody, LOC100438523 antibody
- 背景
- Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels, each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2). Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins (3).Synonyms: Cortbp1, KIAA1650, PSAP2, ProSAP1, ProSAP2, SH3 and multiple ankyrin repeat domains protein, SPANK-3, SSTRIP, Shank1, Shank2, Shank3
- 基因ID
- 171093
- UniProt
- Q9QX74
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