MGMT 抗体
Quick Overview for MGMT 抗体 (ABIN4911931)
抗原
See all MGMT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人
-
纯化方法
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
-
免疫原
- Purified His-tagged MGMT protein was used to produced this monoclonal antibody.
-
亚型
- IgG1
-
-
-
-
应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IF() -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
-
别名
- MGMT
-
背景
-
Synonyms: Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase
Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
-
基因ID
- 4255
-
UniProt
- P16455
-
途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
-