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- 抗原 See all ELAVL1 抗体
- ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ELAVL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- 免疫原
- This ELAVL1 monoclonal antibody is generated from mouse immunized with ELAVL1 recombinant protein.
- 克隆位点
- 4C3
- 亚型
- IgG1
- Top Product
- Discover our top product ELAVL1 Primary Antibody
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anti-ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) antibody
KO Validated ELAVL1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) (AA 1-100) antibodyELAVL1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4G8 unconjugated
anti-ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) antibodyKO Validated ELAVL1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) (AA 1-100) antibodyELAVL1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) (AA 1-326) antibodyELAVL1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) antibodyELAVL1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22938 unconjugated
anti-ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) (AA 1-101) antibodyELAVL1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4G8 unconjugated
anti-ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) antibodyELAVL1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) antibodyELAVL1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1) (AA 1-326) antibodyELAVL1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:300-5000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))
- 别名
- ELAVL1 (ELAVL1 产品)
- 别名
- ELAV1 antibody, HUR antibody, Hua antibody, MelG antibody, HuR antibody, 2410055N02Rik antibody, W91709 antibody, elra antibody, fa25f08 antibody, fb59a02 antibody, fc60g02 antibody, hua antibody, wu:fa25f08 antibody, wu:fb59a02 antibody, wu:fc60g02 antibody, zHuA antibody, Elavl1 antibody, Xel-1 antibody, elav1 antibody, elrA antibody, hur antibody, melg antibody, p36 antibody, ElrA antibody, elavl1 antibody, elavl1-a antibody, elavl1-b antibody, ELAV like RNA binding protein 1 antibody, ELAV-like protein 1 antibody, ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) antibody, ELAV like RNA binding protein 1a antibody, ELAV like RNA binding protein 1 L homeolog antibody, ELAV like RNA binding protein 1 S homeolog antibody, ELAVL1 antibody, Elavl1 antibody, elav1 antibody, elavl1a antibody, elavl1.L antibody, elavl1.S antibody
- 背景
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Synonyms: HUR, Hua, MelG, ELAV1, ELAV-like protein 1, Hu-antigen R, ELAVL1
Background: RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability (PubMed:14517288, PubMed:18285462). Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation (By similarity). Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs (PubMed:8626503, PubMed:17632515, PubMed:18285462, PubMed:23519412). Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro (PubMed:8626503). With ZNF385A, binds the 3'-UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind with ZNF385A the CCNB1 mRNA (By similarity).
- 基因ID
- 1994
- UniProt
- Q15717
- 途径
- AMPK Signaling
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