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DDR2 抗体

DDR2 适用: 人 WB 宿主: 小鼠 Monoclonal 3E5 unconjugated
产品编号 ABIN4908649
发货至: 中国
  • 抗原 See all DDR2 抗体
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    适用
    • 42
    • 25
    • 2
    • 1
    宿主
    • 49
    • 6
    小鼠
    克隆类型
    • 49
    • 6
    单克隆
    标记
    • 29
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DDR2 antibody is un-conjugated
    应用范围
    • 41
    • 34
    • 21
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    纯化方法
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    免疫原
    This DDR2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from human DDR2.
    克隆位点
    3E5
    亚型
    IgG1
    Top Product
    Discover our top product DDR2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    别名
    DDR2 (DDR2 产品)
    别名
    MIG20a antibody, NTRKR3 antibody, TKT antibody, TYRO10 antibody, AW495251 antibody, Ntrkr3 antibody, tyro10 antibody, DDR2 antibody, Tyro10 antibody, ddr2 antibody, si:ch211-193c2.1 antibody, discoidin domain receptor tyrosine kinase 2 antibody, discoidin domain receptor family, member 2 antibody, discoidin domain receptor family, member 2, like antibody, DDR2 antibody, Ddr2 antibody, ddr2l antibody
    背景

    Synonyms: TKT, MIG20a, NTRKR3, TYRO10, Discoidin domain-containing receptor 2, Discoidin domain receptor 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10, CD167b, DDR2

    Background: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.

    基因ID
    4921
    UniProt
    Q16832
    途径
    RTK signaling
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