ATG4D 抗体
Our Local Distributor
北京 101111
Quick Overview for ATG4D 抗体 (ABIN4906368)
抗原
See all ATG4D 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人
-
纯化方法
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
-
免疫原
- This ATG4D monoclonal antibody is generated from mouse immunized with ATG4D recombinant protein.
-
亚型
- IgG1
-
-
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 441-470), (C-Term) antibody
ATG4D 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB7567 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 14-43) antibodyATG4D 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 14-43), (N-Term) antibodyATG4D 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7563 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 381-474) antibodyATG4D 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (C-Term) antibodyATG4D 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 220-249) antibodyATG4D 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7565 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 227-257) antibodyATG4D 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 326-356) antibodyATG4D 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11866 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (Center) antibodyATG4D 适用: 人, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 42-71), (N-Term) antibodyATG4D 适用: 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB14788 unconjugated
-
-
应用备注
- WB 1:300-5000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C for 12 months.
-
有效期
- 12 months
-
-
- ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
-
别名
- ATG4D
-
背景
-
Synonyms: APG4D, AUTL4, APG4-D, Cysteine protease ATG4D, AUT-like 4 cysteine endopeptidase, Autophagin-4, Autophagy-related cysteine endopeptidase 4, Autophagy-related protein 4 homolog D, ATG4D
Background: Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
-
基因ID
- 84971
-
UniProt
- Q86TL0
-
途径
- Autophagy
抗原
-
