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- 抗原 See all TGFBR3 抗体
- TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TGFBR3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- Transforming growth factor-β (TGF-β) superfamily members are critical regulators of cell proliferation and differentiation, developmental patterning and morphogenesis, and disease pathogenesis (1-4). TGF-β elicits signaling through three cell surface receptors: type I (RI), type II (RII), and type III (RIII). Type I and type II receptors are serine/threonine kinases that form a heteromeric complex. In response to ligand binding, the type II receptors form a stable complex with the type I receptors allowing phosphorylation and activation of type I receptor kinases (5). The type III receptor, also known as betaglycan, is a transmembrane proteoglycan with a large extracellular domain that binds TGF-β with high affinity but lacks a cytoplasmic signaling domain (6,7). Expression of the type III receptor can regulate TGF-β signaling through presentation of the ligand to the signaling complex. The only known direct TGF-β signaling effectors are the Smad family proteins, which transduce signals from the cell surface directly to the nucleus to regulate target gene transcription (8,9).
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human TGFBR3.
- 亚型
- IgG
- Top Product
- Discover our top product TGFBR3 Primary Antibody
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anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 147-328) antibody
TGFBR3 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1C5H11 unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 147-328) antibodyTGFBR3 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 1C5H11 unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 469-724) antibodyTGFBR3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 140-340) antibodyTGFBR3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 285-319) antibodyTGFBR3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB57596 unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (Internal Region) antibodyVerified TGFBR3 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 210-465) antibodyTGFBR3 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (Extracellular Domain) antibodyTGFBR3 适用: 小鸡 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (Tyr160) antibodyTGFBR3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (C-Term) antibodyTGFBR3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C.
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- 抗原
- TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
- 别名
- TGFBR3 (TGFBR3 产品)
- 别名
- TGFBR3 antibody, DKFZp469I0915 antibody, BGCAN antibody, betaglycan antibody, 1110036H20Rik antibody, AU015626 antibody, AW215636 antibody, TBRIII antibody, transforming growth factor beta receptor 3 antibody, transforming growth factor, beta receptor III antibody, TGFBR3 antibody, tgfbr3 antibody, Tgfbr3 antibody
- 基因ID
- 7049
- UniProt
- Q03167
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