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PCSK2 抗体

PCSK2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4904707
发货至: 中国
  • 抗原 See all PCSK2 抗体
    PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
    适用
    • 26
    • 25
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 41
    • 4
    • 1
    克隆类型
    • 42
    • 4
    多克隆
    标记
    • 25
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCSK2 antibody is un-conjugated
    应用范围
    • 38
    • 18
    • 13
    • 13
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    产品特性
    This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The protein undergoes an initial autocatalytic processing event and interacts with a neuroendocrine secretory protein in the ER, exits the ER and sorts to secretory granules, where it is cleaved and catalytically activated during intracellular transport. The encoded protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2014]
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human PCSK2.
    亚型
    IgG
    Top Product
    Discover our top product PCSK2 Primary Antibody
  • 应用备注
    WB 1:1000-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C.
  • 抗原
    PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
    别名
    PCSK2 (PCSK2 产品)
    别名
    NEC 2 antibody, NEC-2 antibody, NEC2 antibody, PC2 antibody, SPC2 antibody, PCSK2 antibody, 6330411F23Rik antibody, AI839700 antibody, Nec-2 antibody, Nec2 antibody, Phpp-2 antibody, pc2 antibody, nec2 antibody, spc2 antibody, pcsk2 antibody, pcsk2-A antibody, proprotein convertase subtilisin/kexin type 2 antibody, proprotein convertase subtilisin/kexin type 2 L homeolog antibody, PCSK2 antibody, pcsk2 antibody, Pcsk2 antibody, pcsk2.L antibody
    基因ID
    5126
    UniProt
    P16519
    途径
    Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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