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- 抗原 See all MARCKS 抗体
- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MARCKS antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- The expression of a major cellular substrate for protein kinase C, the MARCKS protein, is regulated in a cell-, tissue-, and developmental stage-specific fashion, in addition, this expression can be stimulated acutely by various cytokines in certain cell types (1). MARCKS) binds calmodulin and is a predominant, specific substrate of PKC which is phosphorylated during macrophage and neutrophil activation, growth factor-dependent mitogenesis and neurosecretion, it is redistributed from plasma membrane to cytoplasm when phosphorylated and is involved in leukocyte motility. It has been reported that MARCKS is a filamentous (F) actin crosslinking protein, with activity that is inhibited by PKC-mediated phosphorylation and by binding to calcium-calmodulin. MARCKS may be a regulated crossbridge between actin and the plasma membrane, and modulation of the actin crosslinking activity of the MARCKS protein by calmodulin and phosphorylation represents a potential convergence of the calcium-calmodulin and PKC signal transduction pathways in the regulation of the actin cytoskeleton (2).
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human MARCKS.
- 亚型
- IgG
- Top Product
- Discover our top product MARCKS Primary Antibody
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anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (AA 2-65) antibody
MARCKS 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C2 unconjugated
anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (AA 1-100) antibodyMARCKS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (pSer170) antibodyMARCKS 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (pSer162) antibodyMARCKS 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (pSer158) antibodyMARCKS 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (C-Term) antibodyMARCKS 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) antibodyMARCKS 适用: 哺乳动物 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (Internal Region) antibodyMARCKS 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (Ser162.) antibodyMARCKS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (pSer152), (Ser156) antibodyMARCKS 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C.
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- 抗原
- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
- 别名
- MARCKS (MARCKS 产品)
- 别名
- 80K-L antibody, MACS antibody, PKCSL antibody, PRKCSL antibody, KINC antibody, Macs antibody, marcks antibody, MGC89127 antibody, MARCKS antibody, macs antibody, wu:fb55c06 antibody, wu:fb92d04 antibody, wu:fc19b04 antibody, wu:fc44a10 antibody, zgc:110235 antibody, fc34g03 antibody, fc38c06 antibody, wu:fc34g03 antibody, wu:fc38c06 antibody, zgc:109978 antibody, myristoylated alanine rich protein kinase C substrate antibody, myristoylated alanine-rich protein kinase C substrate antibody, methyl binding domain106 antibody, myristoylated alanine-rich protein kinase C substrate b antibody, myristoylated alanine-rich protein kinase C substrate S homeolog antibody, myristoylated alanine-rich protein kinase C substrate a antibody, MARCKS antibody, Marcks antibody, marcks antibody, mbd106 antibody, marcksb antibody, marcks.S antibody, marcksa antibody
- 基因ID
- 4082
- UniProt
- P29966
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