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EEA1 抗体

EEA1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4903538
发货至: 中国
  • 抗原 See all EEA1 抗体
    EEA1 (Early Endosome Antigen 1 (EEA1))
    适用
    • 75
    • 35
    • 28
    • 16
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    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 53
    • 17
    • 3
    • 2
    • 1
    克隆类型
    • 59
    • 17
    多克隆
    标记
    • 44
    • 4
    • 3
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This EEA1 antibody is un-conjugated
    应用范围
    • 40
    • 19
    • 13
    • 13
    • 12
    • 10
    • 8
    • 8
    • 6
    • 3
    • 1
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    Western Blotting (WB)
    产品特性
    EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking (1-2). The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol-3-phosphate (PtdIns(3)P), targeting EEA1 to early endosomes (3). The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin (4-6). Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion (7).1.Mu, F.T. et al. (1995) J. Biol. Chem. 270, 13503-13511.2.Christoforidis, S. et al. (1999) Nature 397, 621-625.3.Gaullier, J.M. et al. (1998) Nature 394, 432-433.4.Patki, V. et al. (1997) Proc. Natl. Acad. Sci. USA 94, 7326-7330.5.Lawe, D.C. et al. (2003) Mol. Biol. Cell 14, 2935-2945.6.Simonsen, A. et al. (1998) Nature 394, 494-498.7.McBride, H.M. et al. (1999) Cell 98, 377-386.
    纯化方法
    Affinity purification
    免疫原
    Recombinant Protein of human EEA1.
    亚型
    IgG
    Top Product
    Discover our top product EEA1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C.
  • 抗原
    EEA1 (Early Endosome Antigen 1 (EEA1))
    别名
    EEA1 (EEA1 产品)
    别名
    MST105 antibody, MSTP105 antibody, ZFYVE2 antibody, im:7151048 antibody, si:ch211-276p10.2 antibody, A430109M19Rik antibody, B230358H09Rik antibody, early endosome antigen 1 antibody, early endosome antigen 1 S homeolog antibody, EEA1 antibody, eea1 antibody, Eea1 antibody, eea1.S antibody
    基因ID
    8411
    UniProt
    Q15075
    途径
    Toll-Like Receptors Cascades
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