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BCR 抗体
BCR
适用: 人, 小鼠, 大鼠
WB, IHC
宿主: 兔
Polyclonal
unconjugated
BCR抗体详情
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抗原
See all BCR 抗体
BCR
(Breakpoint Cluster Region (BCR))
适用
All reactivities for BCR 抗体
人, 小鼠, 大鼠
宿主
All hosts for BCR 抗体
兔
克隆类型
All clonalities for BCR 抗体
多克隆
标记
All conjugates for BCR 抗体
This BCR antibody is un-conjugated
应用范围
All applications for BCR 抗体
Western Blotting (WB), Immunohistochemistry (IHC)
产品特性
The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.
纯化方法
Affinity purification
免疫原
Recombinant protein of human BCR.
亚型
IgG
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使用细节
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应用备注
WB 1:500-1:2000 , IHC 1:50-1:100
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20°C.
BCR目标详情
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抗原
BCR
(Breakpoint Cluster Region (BCR))
别名
BCR (BCR 产品 )
别名
si:dkey-83d9.7 antibody, zK83D9.7 antibody, BCR antibody, ALL antibody, BCR1 antibody, CML antibody, D22S11 antibody, D22S662 antibody, PHL antibody, 5133400C09Rik antibody, AI561783 antibody, AI853148 antibody, mKIAA3017 antibody, breakpoint cluster region antibody, BCR, RhoGEF and GTPase activating protein antibody, bcr antibody, BCR antibody, Bcr antibody
基因ID
613
UniProt
P11274
途径
Regulation of Leukocyte Mediated Immunity , Platelet-derived growth Factor Receptor Signaling
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