AANAT 抗体
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- 抗原 See all AANAT 抗体
- AANAT (Aralkylamine N-Acetyltransferase (AANAT))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AANAT antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human AANAT
- 亚型
- IgG
- Top Product
- Discover our top product AANAT Primary Antibody
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- 应用备注
- WB 1:500 - 1:1000
- 说明
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Highly expressed in pineal gland and at lower levels in the retina, Weak expression in several brain regions and in the pituitary gland
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- AANAT (Aralkylamine N-Acetyltransferase (AANAT))
- 别名
- AANAT (AANAT 产品)
- 别名
- DSPS antibody, SNAT antibody, AA-NAT antibody, Nat4 antibody, Nat-2 antibody, Snat antibody, aralkylamine N-acetyltransferase antibody, arylalkylamine N-acetyltransferase antibody, AANAT antibody, Aanat antibody
- 背景
- The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 23.344 kDa
- 基因ID
- 15
- UniProt
- Q16613
- 途径
- Photoperiodism
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