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AANAT 抗体

AANAT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4902802
发货至: 中国
  • 抗原 See all AANAT 抗体
    AANAT (Aralkylamine N-Acetyltransferase (AANAT))
    适用
    • 37
    • 18
    • 17
    • 1
    宿主
    • 38
    克隆类型
    • 38
    多克隆
    标记
    • 11
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AANAT antibody is un-conjugated
    应用范围
    • 20
    • 18
    • 14
    • 14
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human AANAT
    亚型
    IgG
    Top Product
    Discover our top product AANAT Primary Antibody
  • 应用备注
    WB 1:500 - 1:1000
    说明

    Highly expressed in pineal gland and at lower levels in the retina, Weak expression in several brain regions and in the pituitary gland

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20C. Avoid freeze / thaw cycles.
  • 抗原
    AANAT (Aralkylamine N-Acetyltransferase (AANAT))
    别名
    AANAT (AANAT 产品)
    别名
    DSPS antibody, SNAT antibody, AA-NAT antibody, Nat4 antibody, Nat-2 antibody, Snat antibody, aralkylamine N-acetyltransferase antibody, arylalkylamine N-acetyltransferase antibody, AANAT antibody, Aanat antibody
    背景
    The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    23.344 kDa
    基因ID
    15
    UniProt
    Q16613
    途径
    Photoperiodism
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