ISG15 抗体 (AA 2-157)
Quick Overview for ISG15 抗体 (AA 2-157) (ABIN4886638)
抗原
See all ISG15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-157
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原理
- Anti-ISG15 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-ISG15 Antibody Picoband® (ABIN4886638). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ISG15 recombinant protein (Position: G2-G157). Human ISG15 shares 65.8% amino acid (aa) sequence identity with mouse ISG15.
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亚型
- IgG
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anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 1-165) antibody
ISG15 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 1-165) antibodyISG15 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (Middle Region) antibodyISG15 适用: 人, 兔, Cow, 犬, 马, Pig, 绵羊, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 31-61) antibodyISG15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) antibodyISG15 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 31-61), (N-Term) antibodyISG15 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB02791 unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 39-68), (N-Term) antibodyISG15 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) antibodyISG15 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 80-129) antibodyISG15 适用: 人, 兔, Cow, 犬, 马, Pig, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (C-Term) antibodyISG15 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: ISG15 ISG15 ubiquitin-like modifier". 2. Blomstrom DC, Fahey D, Kutny R, Korant BD, Knight E Jr (Aug 1986). "Molecular characterization of the interferon-induced 15- kDa protein. Molecular cloning and nucleotide and amino acid sequence". J Biol Chem261 (19): 8811-6. 3. Morales, David J., Lenschow, Deborah J. (December 2013). "The Antiviral Activities of ISG15".Journal of Molecular Biology 425 (24): 4995-5008. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ISG15 (ISG15 Ubiquitin-Like Modifier (ISG15))
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别名
- ISG15
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背景
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Synonyms: Ubiquitin-like protein ISG15,Interferon-induced 15 kDa protein,Interferon-induced 17 kDa protein,IP17,Ubiquitin cross-reactive protein,hUCRP,ISG15,G1P2, UCRP,
Tissue Specificity: Detected in lymphoid cells, striated and smooth muscle, several epithelia and neurons. Expressed in neutrophils, monocytes and lymphocytes. Enhanced expression seen in pancreatic adenocarcinoma, endometrial cancer, and bladder cancer, as compared to non-cancerous tissue. In bladder cancer, the increase in expression exhibits a striking positive correlation with more advanced stages of the disease. .
Background: Interferon-stimulated gene 15 (ISG15) is a 17 kDA secreted protein that in humans is encoded by the ISG15 gene. The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, ion of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted.
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分子量
- 15 kDa
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基因ID
- 9636
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UniProt
- P05161
抗原
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