CASR 抗体 (AA 926-1078)
(1 reference)-
- 抗原 See all CASR 抗体
- CASR (Calcium-Sensing Receptor (CASR))
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抗原表位
- AA 926-1078
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CASR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Extracellular calcium-sensing receptor(CASR) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Extracellular calcium-sensing receptor(CASR) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: calcium sensing receptor
Protein Name: Extracellular calcium-sensing receptor - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived human CASR recombinant protein (Position: Q926-S1078). Human CASR shares 80.5% and 78.6% amino acid (aa) sequence identity with mouse and rat CASR, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product CASR Primary Antibody
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anti-Calcium-Sensing Receptor (CASR) (AA 874-1088) antibody
CASR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (pThr888) antibodyCASR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 121-220) antibodyCASR 适用: Pig WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (C-Term) antibodyCASR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) antibodyCASR 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 216-229), (Extracellular) antibodyCASR 适用: 人 WB, IHC, IF, FACS, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 863-1079) antibodyCASR 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) antibodyCASR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 260-287) antibodyCASR 适用: 小鼠 WB 宿主: 兔 Polyclonal RB41198 unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 1-100) antibody (Alkaline Phosphatase (AP))CASR 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Evaluation of a TPTX model induced by ischemia." in: Experimental animals, Vol. 66, Issue 4, pp. 345-356, (2018) (PubMed).
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: "Evaluation of a TPTX model induced by ischemia." in: Experimental animals, Vol. 66, Issue 4, pp. 345-356, (2018) (PubMed).
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- 抗原
- CASR (Calcium-Sensing Receptor (CASR))
- 别名
- CASR (CASR 产品)
- 背景
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The calcium-sensing receptor (CaSR) is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
Synonyms: Ca sensing receptor | CAR | CaSR | EIG8 | EIG 8 | FHH | FIH | GPRC2A | HHC | HHC1 | NSHPT | PCAR 1 | PCaR1 | P41180 - 基因ID
- 846
- UniProt
- P41180
- 途径
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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