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BCL2L1 抗体 (Middle Region)

Name: BCL2L1 抗体 (Middle Region)
SKU: ABIN4886480
Availability: OutOfStock

This anti-BCL2L1 antibody is a 兔多克隆 antibody detecting BCL2L1 in WB, IHC, FACS 和 ICC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

Western blot analysis of Bcl-X using anti- Bcl-X antibody . (BCL2L1 抗体 (Middle Region))

1 image

(2 references)

产品编号 ABIN4886480

发货至: 中国

Quick Overview for BCL2L1 抗体 (Middle Region) (ABIN4886480)

抗原

See all BCL2L1 抗体

BCL2L1 (BCL2-Like 1 (BCL2L1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This BCL2L1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Discover our top product BCL2L1 Primary Antibody

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AA 75-105, Middle Region

原理

Anti-Bcl-X/BCL2L1 Antibody Picoband®

序列

LDAREVIPMA AVKQALREAG DEFELRYRRA F

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Bcl-X/BCL2L1 Antibody Picoband® (ABIN4886480). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human Bcl-X, identical to the related mouse and rat sequences.

亚型

IgG
anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibody
BCL2L1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3E2-2A5 unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 1-120) antibody
BCL2L1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) antibody
BCL2L1 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibody
BCL2L1 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibody
BCL2L1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 2-212) antibody
BCL2L1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 1-233) antibody
BCL2L1 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 81-200) antibody
BCL2L1 适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (AA 1-209) antibody
BCL2L1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Like 1 (BCL2L1) (N-Term) antibody
BCL2L1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry, 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human1. "Entrez Gene: BCL2L1 BCL2-like 1". 2. Boise LH, González-García M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nuñez G, Thompson CB (Aug 1993). "bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death". Cell 74(4): 597-608.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Cui, Li, Xu, Zhang, Sun, Chen: "Emodin alleviates severe acute pancreatitis-associated acute lung injury by decreasing pre-B-cell colony-enhancing factor expression and promoting polymorphonuclear neutrophil apoptosis." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 5121-5128, (2018) (PubMed).

Zhou, Zhang, Li, Hao, Liu, Wang: "Azithromycin synergistically enhances anti-proliferative activity of vincristine in cervical and gastric cancer cells." in: Cancers, Vol. 4, Issue 4, pp. 1318-32, (2013) (PubMed).
抗原

BCL2L1 (BCL2-Like 1 (BCL2L1))

别名

BCL2L1

背景

Synonyms: Bcl-2-like protein 1,Bcl2-L-1,Apoptosis regulator Bcl-X,BCL2L1,BCL2L, BCLX,
Tissue Specificity: Bcl-X (S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X (L) is found in tissues containing long-lived postmitotic cells, such as adult brain.
Background: Bcl-2-like protein 1, also known as Bcl-X, is a protein that in humans is encoded by the BCL2L1 gene. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform (Bcl-xL) acts as an apoptotic inhibitor and the shorter form (Bcl-xS) acts as an apoptotic activator.

分子量

29 kDa, 60 kDa

基因ID

598

UniProt

Q07817

途径

Apoptosis, Negative Regulation of intrinsic apoptotic Signaling