FBXW7 抗体 (HRP)
Quick Overview for FBXW7 抗体 (HRP) (ABIN4880105)
抗原
See all FBXW7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises F-box/WD repeat-containing protein 7 (Fbxw7), which is also known as cdc4 and SEL-10. The FBW7/Cdc4 F-box protein was first recognized by its ability to bind cyclin E and the SCF (FBW7) is now known to target c-Myc, c-Jun and Notch for degradation in addition to its role in cyclin E proteolysis. FBW7 negatively regulates several key oncoproteins and is a tumour suppressor that is mutated in a wide spectrum of human cancers.
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纯化方法
- Purified on protein A from tissue culture supernatant.
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免疫原
- Synthetic peptide of human sequence
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亚型
- IgG1
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anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibody
FBXW7 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 501-600) antibodyFBXW7 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D1 unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-627) antibodyFBXW7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 279-515) antibodyFBXW7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-707) antibodyFBXW7 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibodyFBXW7 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 兔, 豚鼠, 马, 斑马鱼, Drosophila melanogaster, 猴, 非洲爪蟾, Hamster, Bat, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 251-300) antibodyFBXW7 适用: 小鼠, 大鼠, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-708) antibodyFBXW7 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D1 unconjugated
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应用备注
- Optimal antibody dilution should be determined by titration
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说明
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Myeloma, fusion partnersCells from immunized mice were fused with the Sp2/0-Ag.14 myeloma cell line
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Purified IgG conjugated to Horseradish Peroxidase using Innova Biosciences Lightning-Link ®, supplied in Phosphate buffered saline (PBS) containing 0.01 % Thiomersal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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别名
- Fbxw7/Cdc4
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基因ID
- 55294, 50754
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OMIM
- 606278
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途径
- Notch Signaling, EGFR Signaling Pathway
抗原
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