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2B4 抗体 (Internal Region, pTyr271)

CD244 适用: 人 WB, IP, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN487961
发货至: 中国
  • 抗原 See all 2B4 (CD244) 抗体
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    抗原表位
    • 16
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region, pTyr271
    适用
    • 61
    • 25
    • 12
    宿主
    • 53
    • 8
    • 4
    山羊
    克隆类型
    • 55
    • 10
    多克隆
    标记
    • 28
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This 2B4 antibody is un-conjugated
    应用范围
    • 56
    • 26
    • 26
    • 25
    • 20
    • 9
    • 6
    • 6
    • 6
    • 5
    • 4
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    序列
    c-EFLTIPYEDV KD
    特异性
    This antibody recognizes CD244.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_057466.1.
    Top Product
    Discover our top product CD244 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/64000. Western blot: Approx 75 kDa band observed in Human Natural Killer (NK) cell lysates afterimmunoprecipitation with mouse monoclonal antibody C1.7 coupled to Protein G agarose(calculated MW of 41.5 kDa according to NP_057466.1). We do note that CD244 is aglycoprotein which makes a higher size band to be expected. Recommended concentration: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    别名
    CD244 (CD244 产品)
    别名
    CD244 antibody, 2B4 antibody, NAIL antibody, NKR2B4 antibody, Nmrk antibody, SLAMF4 antibody, C9.1 antibody, F730046O15Rik antibody, Ly90 antibody, CD244 molecule antibody, CD244 natural killer cell receptor 2B4 antibody, CD244 antibody, Cd244 antibody
    背景
    CD244 is expressed on all human NK cells, a subpopulation of T cells, basophils and monocytes. CD244 activates NK cell mediated cytotoxicity, induces secretion of IFN-gamma and matrix metalloproteinases, and NK cell invasiveness. Although there have been several molecules shown to interact with CD244, the signaling mechanism ofCD244-mediated activation of NK cells is still unknown. It is a high affinity receptor for CD48.Synonyms: NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B4, Natural killer cell receptor 2B4
    基因ID
    51744
    NCBI登录号
    NP_057466
    UniProt
    Q9BZW8
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