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FBXW7 抗体

FBXW7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4620357
发货至: 中国
  • 抗原 See all FBXW7 抗体
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    适用
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    宿主
    • 54
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    克隆类型
    • 57
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    多克隆
    标记
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    This FBXW7 antibody is un-conjugated
    应用范围
    • 56
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    Western Blotting (WB)
    特异性
    This antibody detects FBXW7, widely expressed.
    纯化方法
    Affinty chromatograpghy
    免疫原
    Synthetic peptide dervied from the human FBXW7 protein
    Top Product
    Discover our top product FBXW7 Primary Antibody
  • 应用备注
    Western blot (1: 400 starting dilution).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
  • 抗原
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    别名
    FBXW7 (FBXW7 产品)
    别名
    cdc4 antibody, AGO antibody, CDC4 antibody, FBW6 antibody, FBW7 antibody, FBX30 antibody, FBXO30 antibody, FBXW6 antibody, SEL-10 antibody, SEL10 antibody, hAgo antibody, hCdc4 antibody, 1110001A17Rik antibody, Cdc4 antibody, Fbw7 antibody, Fbwd6 antibody, Fbx30 antibody, Fbxo30 antibody, Fbxw6 antibody, F-box and WD repeat domain containing 7 antibody, F-box and WD-40 domain protein 7 antibody, Fbxw7 antibody, FBXW7 antibody, fbxw7 antibody
    背景
    Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.Synonyms: Archipelago homolog, F-box and WD-40 domain-containing protein 7, F-box protein FBX30, F-box/WD repeat-containing protein 7, FBW7, FBX30, SEL-10, SEL10, hAgo, hCDC4
    基因ID
    55294
    NCBI登录号
    NP_001013433
    UniProt
    Q969H0
    途径
    Notch Signaling, EGFR Signaling Pathway
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