ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS with 0.09 % (W/V) sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原
CYP7B1
(Cytochrome P450, Family 7, Subfamily B, Polypeptide 1 (CYP7B1))
CYP7B1 antibody, CBAS3 antibody, CP7B antibody, SPG5A antibody, AW261589 antibody, D3Ertd552e antibody, hct-1 antibody, cytochrome P450 family 7 subfamily B member 1 antibody, cytochrome P450, family 7, subfamily B, polypeptide 1 antibody, cytochrome P450, family 7, subfamily b, polypeptide 1 antibody, CYP7B1 antibody, cyp7b1 antibody, Cyp7b1 antibody
背景
CYP7B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.Synonyms: 25-hydroxycholesterol 7-alpha-hydroxylase, Cytochrome P450 7B1, Oxysterol 7-alpha-hydroxylase