DLC1 抗体 (Isoform 1, Isoform 3, N-Term)
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- 抗原 See all DLC1 抗体
- DLC1 (Deleted in Liver Cancer 1 (DLC1))
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抗原表位
- Isoform 1, Isoform 3, N-Term
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适用
- 人, 小鼠, Pig
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This DLC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 序列
- SVAIRKRSWE EHC
- 特异性
- This antibody is expected to recognise isoforms 1 and 3 ( NP_872584.2 and NP_079043.3) but NOT isoform 2 (NP_006085.2).
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Pig.
Species reactivity (tested):Human. - 纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- 免疫原
- Peptide with sequence from the N Terminus of the protein sequence according to NP_872584.2, NP_079043.3. Genename: DLC1
- Top Product
- Discover our top product DLC1 Primary Antibody
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anti-Deleted in Liver Cancer 1 (DLC1) (N-Term) antibody
Verified DLC1 适用: 人, 小鼠 IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (N-Term) antibodyDLC1 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) antibodyDLC1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 204-463) antibodyDLC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (N-Term) antibodyDLC1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) antibodyDLC1 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 1-1528) antibodyDLC1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 1-1528) antibodyDLC1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 1224-1273) antibodyDLC1 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 马, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Liver Cancer 1 (DLC1) (AA 61-110) antibodyDLC1 适用: 人, 小鼠, 大鼠 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: Antibody Detection Limit Dilution: 1/2,000. Western Blot: Preliminary experiments gave an approx 28 kDa band in Human Liver andLung lysates as well as in different epithelial lung cell lines after 0.3 μg/mL antibodystaining. Please note that currently we cannot find an explanation in the literature for theband we observe given the calculated size of 171 kDa according to NP_872584.1 and54.8 kDa according to NP_079043.2 (isotope 3). The 28 kDa band was successfully blockedby incubation with the immunizing peptide. Immunohistochemistry: 5 μg/mL. In paraffin embedded Human Adrenal Gland (Medulla)shows strong reticulate staining in the cytoplasm of medular cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- DLC1 (Deleted in Liver Cancer 1 (DLC1))
- 别名
- ARHGAP7 / DLC1 (DLC1 产品)
- 别名
- ARHGAP7 antibody, HP antibody, STARD12 antibody, p122-RhoGAP antibody, rhogap7 antibody, DLC-1 antibody, StARD12 antibody, Dlc-1 antibody, A730069N07Rik antibody, Arhgap7 antibody, dlc-1 antibody, RhoGAP antibody, Dlc1 antibody, DLC1 Rho GTPase activating protein antibody, DLC1 Rho GTPase activating protein S homeolog antibody, rho GTPase-activating protein 7 antibody, deleted in liver cancer 1 antibody, DLC1 antibody, dlc1.S antibody, dlc1 antibody, LOC100456847 antibody, Dlc1 antibody, LOC100729904 antibody
- 背景
- DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization. DLC1 is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers.Synonyms: Deleted in liver cancer 1 protein, HP protein, KIAA1723, Rho GTPase-activating protein 7, Rho-type GTPase-activating protein 7, STARD12, START domain-containing protein 12, StAR-related lipid transfer protein 12
- 基因ID
- 10395
- NCBI登录号
- NP_006085
- UniProt
- Q96QB1
- 途径
- Tube Formation, Positive Regulation of Endopeptidase Activity
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