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GGCX 抗体 (C-Term)

GGCX 适用: 人, 犬 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN452673
发货至: 中国
  • 抗原 See all GGCX 抗体
    GGCX (gamma-Glutamyl Carboxylase (GGCX))
    抗原表位
    • 15
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 35
    • 22
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 犬
    宿主
    • 48
    • 1
    • 1
    山羊
    克隆类型
    • 50
    多克隆
    标记
    • 15
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GGCX antibody is un-conjugated
    应用范围
    • 25
    • 24
    • 19
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    GGCX antibody AP09596PU-N is expected to recognize both isoforms (NP_000812.2 and NP_001135741.1).
    交叉反应 (详细)
    Species reactivity (expected):Canine (Dog).
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence C-PPESNPDPVHSE, from the C-Terminus of the protein sequence according to NP_000812.2 and NP_001135741.1.
    Top Product
    Discover our top product GGCX Primary Antibody
  • 应用备注
    Peptide ELISA: GGCX Antibody Detection limit dilution 1/32000. Western blot: 0.3-1 μg/mL. Approx 85 kDa band observed in Human Muscle lysates(calculated MW of 85 kDa according to NP_000812.2).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    GGCX (gamma-Glutamyl Carboxylase (GGCX))
    别名
    GGCX (GGCX 产品)
    别名
    GGCX antibody, cb751 antibody, si:ch1073-230p18.3 antibody, zgc:158736 antibody, ggcx antibody, GGC antibody, vkcfd1 antibody, CG13927 antibody, DgammaC antibody, Dmel\\CG13927 antibody, dGC antibody, dgammaC antibody, gammaC antibody, VKCFD1 antibody, gamma-glutamyl carboxylase antibody, gamma-glutamyl carboxylase L homeolog antibody, GGCX antibody, ggcx antibody, GC antibody, sce5891 antibody, ggcx.L antibody, Ggcx antibody
    背景
    Gamma-glutamyl carboxylase GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. GGCX accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP, MIM 112260) and bone matrix protein (MGP, MIM 154870).Synonyms: GC, Gamma-glutamyl carboxylase, Vitamin K gamma glutamyl carboxylase, Vitamin K-dependent gamma-carboxylase
    基因ID
    2677
    NCBI登录号
    NP_000812
    UniProt
    P38435
    途径
    SARS-CoV-2 Protein Interactome
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