KCNQ1 抗体 (AA 2-101)
-
- 抗原 See all KCNQ1 抗体
- KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
-
抗原表位
- AA 2-101
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This KCNQ1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody detects KCNQ1 K+ Channel at ~75 kDa.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat
- 产品特性
- Synonyms: KCNA8, KCNA9, KVLQT1, KQT-like 1, Potassium voltage-gated channel subfamily KQTmember 1, Voltage-gated potassium channel subunit Kv7.1, IKs producing slowvoltage-gated potassium channel subunit alpha KvLQT1
- 纯化方法
- Protein G chromatography
- 免疫原
- Fusion protein amino acid 2-101 of human KCNQ1 (Kv7. 1, KvLQT1
- 克隆位点
- S37A-10
- 亚型
- IgG1
- Top Product
- Discover our top product KCNQ1 Primary Antibody
-
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody
KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) unconjugated
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (HRP)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) HRP
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (FITC)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) FITC
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (Biotin)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) Biotin
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (PE)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) PE
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (APC)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) APC
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (PerCP)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) PerCP
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (Atto 488)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) Atto 488
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (Atto 594)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) Atto 594
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (AA 2-101) antibody (Atto 390)KCNQ1 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N37A-10 (Formerly S37A-10) Atto 390
-
- 应用备注
-
Western blot: 1 - 10 μg/mL (if results are off, try using thelysate without boiling). Immunoprecipitation. Immunohistochemistry on frozen sections: 0.1 - 1.0 μg/mL (Perox).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol and 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
-
- 抗原
- KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
- 别名
- KCNQ1 (KCNQ1 产品)
- 别名
- ATFB1 antibody, ATFB3 antibody, JLNS1 antibody, KCNA8 antibody, KCNA9 antibody, KVLQT1 antibody, Kv1.9 antibody, Kv7.1 antibody, LQT antibody, LQT1 antibody, RWS antibody, SQT2 antibody, WRS antibody, CG12215 antibody, CG12915 antibody, CG33135 antibody, DKCNQ antibody, Dmel\\CG33135 antibody, dKCNQ antibody, kcnq1 antibody, KCNQ1 antibody, kqt-3 antibody, kv7.1 antibody, Kvlqt1 antibody, KvLQT-1 antibody, kcnq1-A antibody, xkvlqt1 antibody, zgc:158384 antibody, AW559127 antibody, Kcna9 antibody, KvLQT1 antibody, potassium voltage-gated channel subfamily Q member 1 antibody, KCNQ potassium channel antibody, potassium voltage-gated channel, KQT-like subfamily, member 1 antibody, potassium channel, voltage gated KQT-like subfamily Q, member 1 antibody, voltage gated potassium channel subunit antibody, potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog antibody, potassium voltage-gated channel, subfamily Q, member 1 antibody, KCNQ1 antibody, KCNQ antibody, kcnq1 antibody, Kcnq1 antibody, kcnq1.L antibody
- 背景
- Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels, each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gate channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2). Specifically, Kv7.1 (KvLQT1) is a potassium channel protein coded for by the gene KCNQ1. Kv7.1 is present in the cell membranes of cardiac muscle tissue and in inner ear neurons (3) among other tissues. In the cardiac cells, Kv7.1 mediates the IKs (or slow delayed rectifying K+) current that contributes to the repolarization of the cell, terminating the cardiac action potential and thereby the heart's contraction (4, 5).Synonyms: IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, KCNA8, KCNA9, KQT-like 1, KVLQT1, Potassium voltage-gated channel subfamily KQT member 1, Voltage-gated potassium channel subunit Kv7.1
- 基因ID
- 3784
- UniProt
- P51787
- 途径
- Negative Regulation of Hormone Secretion, Sensory Perception of Sound
-
