CACNA1D 抗体 (N-Term)
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- 抗原 See all CACNA1D 抗体
- CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))
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抗原表位
- AA 859-875, N-Term
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适用
- 大鼠, 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CACNA1D antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody detects Cav1.3 Ca2+ Channel at ~250 kDa. No cross-reactivity against Cav1.2.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
- 产品特性
- Synonyms: CACH3, CACN4, CACNL1A2, CCHL1A2, Cav1.3, Voltage-dependent L-type calcium channelsubunit alpha-1D, Voltage-gated calcium channel subunit alpha, Calcium channel, L type,alpha-1 polypeptide, isoform 2
- 纯化方法
- Protein G Chromatography
- 免疫原
- Fusion protein amino acids 859-875 (N-Terminal) of rat Cav1. 3 (also known as voltagedependent L-type calcium channel subunit alpha-1D, RAT brain class D and RBD)
- 克隆位点
- S48A-9
- 亚型
- IgG2b
- Top Product
- Discover our top product CACNA1D Primary Antibody
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anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (AA 859-875) antibody
CACNA1D 适用: 大鼠 IHC, WB, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S48 unconjugated
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (AA 859-875) antibody (HRP)CACNA1D 适用: 大鼠 IHC, WB, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S48 HRP
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (AA 859-875) antibody (FITC)CACNA1D 适用: 大鼠 IHC, WB, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S48 FITC
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (AA 859-875) antibody (Biotin)CACNA1D 适用: 大鼠 IHC, WB, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S48 Biotin
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (AA 859-875) antibody (PE)CACNA1D 适用: 大鼠 IHC, WB, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S48 PE
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (AA 859-875) antibody (APC)CACNA1D 适用: 大鼠 IHC, WB, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S48 APC
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (AA 859-875) antibody (PerCP)CACNA1D 适用: 大鼠 IHC, WB, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S48 PerCP
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (AA 859-875) antibody (Atto 488)CACNA1D 适用: 大鼠 IHC, WB, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S48 Atto 488
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (AA 859-875) antibody (Atto 594)CACNA1D 适用: 大鼠 IHC, WB, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S48 Atto 594
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (AA 859-875) antibody (Atto 390)CACNA1D 适用: 大鼠 IHC, WB, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S48 Atto 390
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- 应用备注
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Western blot: 1-10 μg/mL (if results are off, try using the lysate without boiling). Immunoprecipitation. Immunocytochemistry: 0.1 - 1.0 μg/mL (Perox). Immunohistochemistry on frozen sections: 0.1 - 1.0 μg/mL (Perox). Immunflourescence: 1.0 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS pH 7.4 containing 50 % Glycerol and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))
- 别名
- CACNA1D (CACNA1D 产品)
- 别名
- cacna1d antibody, cav1.3a antibody, isl antibody, si:dz136d19.3 antibody, si:dz223c6.1 antibody, ca(v)1.3 antibody, cav1.3 antibody, CACH3 antibody, CACN4 antibody, CACNL1A2 antibody, CCHL1A2 antibody, Cav1.3 antibody, SANDD antibody, 8430418G19Rik antibody, C79217 antibody, Cacnl1a2 antibody, Cchl1a antibody, Cchl1a2 antibody, D-LTCC antibody, calcium channel, voltage-dependent, L type, alpha 1D subunit, a antibody, calcium voltage-gated channel subunit alpha1 D antibody, calcium channel, voltage-dependent, L type, alpha 1D subunit antibody, calcium channel, voltage-dependent, L type, alpha 1D subunit L homeolog antibody, cacna1da antibody, CACNA1D antibody, cacna1d antibody, cacna1d.L antibody, Cacna1d antibody
- 背景
- Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage-gated ion channels, ligand-gated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels, each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2). Specifically, Cav1.3, also known as the calcium channel, voltage-dependent, L type, alpha 1D subunit (CACNA1D), is a human gene. Cav1.3 subunits are primarily expressed in neurons and neuroendocine cells. Some studies suggest however that Cav1.3 is also found in the atria, and may figure prominently in atrial arrhythmias (3). Cav1.3 also carries the primary sensory receptors of the mammalian cochlea, and are also expressed in the electromotile outer hair cells (4).Synonyms: CACH3, CACN4, CACNL1A2, CCHL1A2, Calcium channel, Cav1.3, L type, Voltage-dependent L-type calcium channel subunit alpha-1D, Voltage-gated calcium channel subunit alpha, alpha-1 polypeptide, isoform 2
- 基因ID
- 29716
- UniProt
- P27732
- 途径
- Sensory Perception of Sound
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