CACNA1H 抗体 (AA 1019-1293)
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- 抗原 See all CACNA1H 抗体
- CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))
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抗原表位
- AA 1019-1293
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CACNA1H antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
- 特异性
- This antibody detects Cav3.2 Ca2+ Channel at ~260 kDa. No cross-reactivity against Cav1.3.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 产品特性
- Synonyms: Cav3.2, Voltage-dependent T-type calcium channel subunit alpha-1H, Voltage-gatedcalcium channel subunit alpha Cav3.2, Low-voltage-activated calcium channel alpha1 3.2subunit
- 纯化方法
- Protein G chromatography
- 免疫原
- Fusion protein amino acids 1019-1293 (II-III loop) of human Cav3. 2 (also known asvoltagedependent T-type calcium channel subunit alpha-1H
- 克隆位点
- S55-10
- 亚型
- IgG1
- Top Product
- Discover our top product CACNA1H Primary Antibody
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anti-Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H) (AA 1019-1293) antibody (HRP)
CACNA1H 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N55-10 (Formerly S55-10) HRP
anti-Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H) (AA 1019-1293) antibody (FITC)CACNA1H 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N55-10 (Formerly S55-10) FITC
anti-Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H) (AA 1019-1293) antibody (Biotin)CACNA1H 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N55-10 (Formerly S55-10) Biotin
anti-Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H) (AA 1019-1293) antibody (PE)CACNA1H 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N55-10 (Formerly S55-10) PE
anti-Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H) (AA 1019-1293) antibody (APC)CACNA1H 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N55-10 (Formerly S55-10) APC
anti-Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H) (AA 1019-1293) antibody (PerCP)CACNA1H 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N55-10 (Formerly S55-10) PerCP
anti-Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H) (AA 1019-1293) antibody (Atto 488)CACNA1H 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N55-10 (Formerly S55-10) Atto 488
anti-Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H) (AA 1019-1293) antibody (Atto 594)CACNA1H 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N55-10 (Formerly S55-10) Atto 594
anti-Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H) (AA 1019-1293) antibody (Atto 390)CACNA1H 适用: 人 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal N55-10 (Formerly S55-10) Atto 390
anti-Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H) (AA 581-595), (Intracellular Loop) antibodyCACNA1H 适用: 人, 小鼠, 大鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1 - 10 μg/mL (if results are off, try using the lysate without boiling). Immunoprecipitation. Immunocytochemistry: 0.1 - 1.0 μg/mL (Perox).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol and 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))
- 别名
- CACNA1H (CACNA1H 产品)
- 别名
- CACNA1HB antibody, Cav3.2 antibody, ECA6 antibody, EIG6 antibody, MNCb-1209 antibody, alpha13.2 antibody, calcium voltage-gated channel subunit alpha1 H antibody, calcium channel, voltage-dependent, T type, alpha 1H subunit antibody, CACNA1H antibody, Cacna1h antibody
- 背景
- Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels, each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2). Specifically, Cav3.2 is a protein which in humans is encoded by the CACNA1H gene. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (3, 4). Studies also suggest that the up-regulations of Cav3.2 may participate in the progression of prostate cancer toward an androgen-independent stage (5).Synonyms: Cav3.2, Low-voltage-activated calcium channel alpha1 3.2 subunit, Voltage-dependent T-type calcium channel subunit alpha-1H, Voltage-gated calcium channel subunit alpha Cav3.2
- 基因ID
- 8912
- UniProt
- O95180
- 途径
- C21-Steroid Hormone Metabolic Process
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