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TIMELESS 抗体 (N-Term)

This anti-TIMELESS antibody is a 兔 多克隆 antibody detecting TIMELESS in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN410144
发货至: 中国

Quick Overview for TIMELESS 抗体 (N-Term) (ABIN410144)

抗原

See all TIMELESS 抗体
TIMELESS (Timeless Homolog (TIMELESS))

适用

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宿主

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克隆类型

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多克隆

标记

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This TIMELESS antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    特异性

    Reacts with human 138 kDa protein

    交叉反应

    小鼠, 大鼠

    交叉反应 (详细)

    Cross reacts with proteins from mouse, rat and other species.

    纯化方法

    Antiserum

    免疫原

    Synthetic peptide derived from Nter domain of human hTIM protein

    亚型

    IgG
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    - IHC : 1/50 to 1/200 - WB : 1/100 to 1/1 000

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Must be reconstituted in distilled water.

    储存条件

    4 °C/-20 °C

    储存方法

    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

    有效期

    24 months
  • 抗原

    TIMELESS (Timeless Homolog (TIMELESS))

    别名

    Protein Timeless Homolog (hTIM)

    背景

    Required for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Promotes TIPIN nuclear localiZation. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.

    UniProt

    Q9UNS1

    途径

    Protein targeting to Nucleus, Photoperiodism
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