SUMF1 抗体 (Internal Region)
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- 抗原 See all SUMF1 抗体
- SUMF1 (Sulfatase Modifying Factor 1 (SUMF1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This SUMF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 序列
- c-ETLNPKGPPS GKDR
- 特异性
- This antibody detects SUMF1 / FGE (Internal).
- 交叉反应 （详细）
- Species reactivity (expected):Rat, Dog, CowSpecies reactivity (tested):Human, Mouse
- 纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- 免疫原
- Peptide from the internal region of the protein sequence according to NP_877437.2 . Genename: SUMF1
- Top Product
- Discover our top product SUMF1 Primary Antibody
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anti-Sulfatase Modifying Factor 1 (SUMF1) (AA 113-356) antibody
SUMF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sulfatase Modifying Factor 1 (SUMF1) (AA 303-331), (C-Term) antibodySUMF1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23824 unconjugated
anti-Sulfatase Modifying Factor 1 (SUMF1) (AA 310-339), (C-Term) antibodySUMF1 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Sulfatase Modifying Factor 1 (SUMF1) (Internal Region) antibodyVerified SUMF1 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Sulfatase Modifying Factor 1 (SUMF1) (AA 34-374) antibodySUMF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: antibody detection limit dilution 1: 16000. Western blot: 0.5-2 μg/mL. Approx 37-40 kDa band observed in Mouse Pancreas, Mouse Eyeand Human Kidney lysates (calculated MW of 40.0 kDa according to NP_877437.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- 抗原
- SUMF1 (Sulfatase Modifying Factor 1 (SUMF1))
- 别名
- SUMF1 / FGE (SUMF1 产品)
- 别名
- AAPA3037 antibody, FGE antibody, AA543204 antibody, AI463102 antibody, AI851573 antibody, sulfatase modifying factor 1 antibody, SUMF1 antibody, Sumf1 antibody
- 背景
- SUMF1 is a sulfatase modifying enzyme that oxidizes a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also called C(alpha)-formylglycine. Defects in SUMF1 are the cause of multiple sulfatase deficiency (MSD). MSD is a clinically and biochemically heterogeneous disorder caused by the simultaneous impairment of all sulfatases, due to defective post-translational modification and activation. It combines features of individual sulfatase deficiencies such as metachromatic leukodystrophy, mucopolysaccharidosis, chondrodysplasia punctata, hydrocephalus, ichthyosis, neurologic deterioration and developmental delay. Inheritance is autosomal recessive.Synonyms: C-alpha-formylglycine-generating enzyme 1, Sulfatase-modifying factor 1
- 基因ID
- 285362
- NCBI登录号
- NP_877437
- UniProt
- Q8NBK3
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