NRIP1 抗体 (Internal Region)
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- 抗原 See all NRIP1 抗体
- NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))
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抗原表位
- Internal Region
- 适用
- 人, 大鼠, 小鼠, Cow, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This NRIP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 序列
- c-EKDSPRLTKT NP
- 特异性
- This antibody detects RIP140 / NRIP1 (Internal).
- 交叉反应 （详细）
- Species reactivity (expected):Mouse, Rat, Dog, CowSpecies reactivity (tested):Human
- 纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- 免疫原
- Peptide from the internal region of the protein sequence according to NP_003480.2 . Genename: NRIP1
- Top Product
- Discover our top product NRIP1 Primary Antibody
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anti-Nuclear Receptor Interacting Protein 1 (NRIP1) (C-Term) antibody
NRIP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Interacting Protein 1 (NRIP1) (acLys158) antibodyNRIP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Interacting Protein 1 (NRIP1) (AA 1051-1158) antibodyNRIP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Interacting Protein 1 (NRIP1) (Internal Region) antibodyVerified NRIP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Nuclear Receptor Interacting Protein 1 (NRIP1) (AA 939-1158) antibodyNRIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.5-2 μg/mL. Approx 140 kDa band observed in Human Brain (Cerebellum)lysates (calculated MW of 120 kDa according to NP_003480.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- 抗原
- NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))
- 别名
- NRIP1 (NRIP1 产品)
- 别名
- MGC68665 antibody, NRIP1 antibody, RIP140 antibody, 6030458L20Rik antibody, 8430438I05Rik antibody, 9630050P12 antibody, AA959574 antibody, AW456757 antibody, nuclear receptor interacting protein 1 S homeolog antibody, nuclear receptor interacting protein 1 antibody, circumsporozoite protein antibody, nrip1.S antibody, NRIP1 antibody, nrip1 antibody, Nrip1 antibody, LOC100627733 antibody
- 背景
- RIP140 is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as nuclear receptor interacting protein 1 (NRIP1), this protein modulates transcriptional activity of the estrogen receptor. Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Receptor Interacting Protein 140 (RIP 140) has been shown to enhance estrogen receptor transcriptional activity through the AF2 activation domain in an agonist dependent manner and has also been implicated to be involved in other steroid receptor pathways, including the retinoid pathway. RIP 140 has recently been shown to interact with peroxisome proliferator-activated receptor-alpha (PPAR alpha) and has been proposed to competitively inhibit PPAR alpha interaction with Steroid Receptor Coactivator-1 (SRC-1).Synonyms: Nuclear factor RIP140, Nuclear receptor-interacting protein 1, Receptor-interacting protein 140
- 基因ID
- 8204
- NCBI登录号
- NP_003480
- UniProt
- P48552
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
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