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POGZ 抗体 (N-Term)

The 兔 多克隆 anti-POGZ antibody is suitable to detect POGZ in samples from 人, 小鼠, 大鼠, 犬, Cow, 小鸡, Macaque, Olive Baboon 和 Chimpanzee. It has been validated for WB 和 EIA.
产品编号 ABIN401435
发货至: 中国
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Quick Overview for POGZ 抗体 (N-Term) (ABIN401435)

抗原

See all POGZ 抗体
POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

适用

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人, 小鼠, 大鼠, 犬, Cow, 小鸡, Macaque, Olive Baboon, Chimpanzee

宿主

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克隆类型

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多克隆

标记

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This POGZ antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 5
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    N-Term

    特异性

    This antibody is known to react with Pogz protein.

    交叉反应 (详细)

    Species reactivity (expected):Human, Canine, Cattle, Rat, Chimpanzee, Macaque, Olive Baboon, Chicken, Short-tailed opossum.
    Species reactivity (tested):Mouse.

    纯化方法

    Affinity chromatography

    免疫原

    Synthetic peptide corresponding to a region near the N-terminus of mouse Pogz protein

    亚型

    IgG
  • 应用备注

    ELISA: 1/150,000. Western Blot: 1/3,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.564 mg/mL (by UV absorbance at 280 nm)

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

    别名

    POGZ

    背景

    Pogz is a zinc-finger protein containing at least 8 C2H2 zinc fingers, a CENP-B (centromere protein-B) domain, and a DDE domain found in the bacterial transposase/retroviral integrase family. Members of this family of integrases share structural homologies and show similar catalytic activity to the RAG1 and RAG2 proteins that initiate V(D)J recombination in lymphoid progenitors. Mouse Pogz has a human homolog with a base pair similarity of 90 % and amino acid similarity of 93 % for the full length protein. In humans at least 3 variants have been predicted and they are all similar at the N-terminus. A number of expressed sequence tags (ESTAs) cloned from murine undifferentiated ES cells and Lin-/c-Kit+/Sca-1+ hematopoietic stem cell cDNA libraries correspond to the Pogz gene, further underlining an important function for this gene in stem cells. In mice, deletion of the gene in all tissues early in embryogenesis has been shown to be lethal.Synonyms: KIAA0461, Pogo transposable element with ZNF domain, SUHW5, Suppressor of hairy wing homolog 5, ZNF280E, ZNF635

    基因ID

    229584

    NCBI登录号

    NP_766271

    UniProt

    Q8BZH4
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