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POGZ 抗体 (N-Term)

POGZ 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡, Chimpanzee, Macaque, Olive Baboon WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401435
发货至: 中国
  • 抗原 See all POGZ 抗体
    POGZ (Pogo Transposable Element with ZNF Domain (POGZ))
    抗原表位
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    N-Term
    适用
    • 25
    • 10
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 小鸡, Chimpanzee, Macaque, Olive Baboon
    宿主
    • 24
    • 2
    克隆类型
    • 26
    多克隆
    标记
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POGZ antibody is un-conjugated
    应用范围
    • 14
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is known to react with Pogz protein.
    交叉反应 (详细)
    Species reactivity (expected):Human, Canine, Cattle, Rat, Chimpanzee, Macaque, Olive Baboon, Chicken, Short-tailed opossum.
    Species reactivity (tested):Mouse.
    纯化方法
    Affinity chromatography
    免疫原
    Synthetic peptide corresponding to a region near the N-terminus of mouse Pogz protein
    亚型
    IgG
    Top Product
    Discover our top product POGZ Primary Antibody
  • 应用备注
    ELISA: 1/150,000. Western Blot: 1/3,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.564 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    POGZ (Pogo Transposable Element with ZNF Domain (POGZ))
    别名
    POGZ (POGZ 产品)
    别名
    POGZ antibody, ZNF280E antibody, ZNF635 antibody, ZNF635m antibody, 9530006B08Rik antibody, AU015913 antibody, AU044539 antibody, pogo transposable element with ZNF domain antibody, pogo transposable element derived with ZNF domain antibody, POGZ antibody, pogz antibody, Pogz antibody
    背景
    Pogz is a zinc-finger protein containing at least 8 C2H2 zinc fingers, a CENP-B (centromere protein-B) domain, and a DDE domain found in the bacterial transposase/retroviral integrase family. Members of this family of integrases share structural homologies and show similar catalytic activity to the RAG1 and RAG2 proteins that initiate V(D)J recombination in lymphoid progenitors. Mouse Pogz has a human homolog with a base pair similarity of 90 % and amino acid similarity of 93 % for the full length protein. In humans at least 3 variants have been predicted and they are all similar at the N-terminus. A number of expressed sequence tags (ESTAs) cloned from murine undifferentiated ES cells and Lin-/c-Kit+/Sca-1+ hematopoietic stem cell cDNA libraries correspond to the Pogz gene, further underlining an important function for this gene in stem cells. In mice, deletion of the gene in all tissues early in embryogenesis has been shown to be lethal.Synonyms: KIAA0461, Pogo transposable element with ZNF domain, SUHW5, Suppressor of hairy wing homolog 5, ZNF280E, ZNF635
    基因ID
    229584
    NCBI登录号
    NP_766271
    UniProt
    Q8BZH4
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