This affinity purified antibody is directed against SmarcAL1 protein.
交叉反应 (详细)
Species reactivity (expected):Cross reactivity with SmarcAL1 from other sources is not expected due to significant sequence divergence within the immunogen sequence. Species reactivity (tested):Human.
纯化方法
Immunoaffinity chromatography
免疫原
Synthetic peptide corresponding aa 80-96 of human SmarcAL1 protein
Western blot: 1: 500 - 1: 3,000. ELISA: 1: 16,000 - 1: 64,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
2.0 mg/mL (by UV absorbance at 280 nm)
缓冲液
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
储存条件
4 °C/-20 °C
储存方法
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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背景
SmarcAL1 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a-like 1) is also known as HARP, HepA Related Protein, HHARP, SMARCA like Protein 1 and SWI/SNF Related. SmarcAL1 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.Synonyms: HepA-related protein, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, Sucrose nonfermenting protein 2-like 1