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PTP4A3 抗体

PTP4A3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7265 unconjugated
产品编号 ABIN392854
发货至: 中国
  • 抗原 See all PTP4A3 抗体
    PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
    适用
    • 45
    • 23
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 42
    • 3
    克隆类型
    • 43
    • 2
    多克隆
    标记
    • 23
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTP4A3 antibody is un-conjugated
    应用范围
    • 31
    • 17
    • 10
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This PRL3 antibody is generated from rabbits immunized with a recombinant protein encoding full length of human PRL3.
    克隆位点
    RB7265
    亚型
    Ig Fraction
    Top Product
    Discover our top product PTP4A3 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
    别名
    PRL3 (PTP4A3 产品)
    别名
    PRL-3 antibody, PRL-R antibody, PRL3 antibody, wu:fc54b05 antibody, wu:fv52d11 antibody, zgc:77109 antibody, prl-3 antibody, prl3 antibody, ptpcaax3 antibody, PTP4A3 antibody, AV088979 antibody, Prl-3 antibody, pPtp4a3 antibody, protein tyrosine phosphatase type IVA, member 3 antibody, protein tyrosine phosphatase type IVA, member 3 L homeolog antibody, protein tyrosine phosphatase 4a3 antibody, PTP4A3 antibody, ptp4a3 antibody, ptp4a3.L antibody, Ptp4a3 antibody
    背景
    The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. PRL-3 expression was found to be up-regulated in human liver carcinoma compared with normal liver. Its expression in colorectal cancers may contribute to the establishment of liver metastasis. In a different study, PRL-3 is found to be expressed in tumor metastasis and vasculature, regardless of the tumor source.
    分子量
    19535
    基因ID
    11156
    NCBI登录号
    NP_009010, NP_116000
    UniProt
    O75365
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