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BAI1 抗体 (C-Term)

This anti-BAI1 antibody is a 兔 多克隆 antibody detecting BAI1 in WB, IHC (p) 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN392804
发货至: 中国

Quick Overview for BAI1 抗体 (C-Term) (ABIN392804)

抗原

See all BAI1 抗体
BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This BAI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB02096
  • 抗原表位

    • 15
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    AA 1537-1567, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This BAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1537-1567 amino acids from the C-terminal region of human BAI1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

    别名

    BAI1

    背景

    Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas.

    分子量

    173501

    基因ID

    575

    NCBI登录号

    NP_001693

    UniProt

    O14514

    途径

    p53 Pathway
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