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TRPM6 抗体 (AA 317-348)

TRPM6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3407 unconjugated
产品编号 ABIN392616
发货至: 中国
  • 抗原 See all TRPM6 抗体
    TRPM6 (Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))
    抗原表位
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 317-348
    适用
    • 23
    • 17
    • 17
    宿主
    • 24
    • 1
    克隆类型
    • 25
    多克隆
    标记
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRPM6 antibody is un-conjugated
    应用范围
    • 13
    • 9
    • 8
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This TRPM6 (CHAK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-348 amino acids from the Central region of human TRPM6 (CHAK2).
    克隆位点
    RB3407
    亚型
    Ig Fraction
    Top Product
    Discover our top product TRPM6 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Furukawa, Fujii, Manabe, Matsunaga, Endo, Hasegawa, Ito, Yamaguchi, Yamazaki, Ikari: "Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor." in: Journal of cellular physiology, Vol. 232, Issue 10, pp. 2841-2850, (2017) (PubMed).

    Ikari, Okude, Sawada, Takahashi, Sugatani, Miwa: "Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 377, Issue 4-6, pp. 333-43, (2008) (PubMed).

    Ikari, Okude, Sawada, Yamazaki, Sugatani, Miwa: "TRPM6 expression and cell proliferation are up-regulated by phosphorylation of ERK1/2 in renal epithelial cells." in: Biochemical and biophysical research communications, Vol. 369, Issue 4, pp. 1129-33, (2008) (PubMed).

  • 抗原
    TRPM6 (Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))
    别名
    TRPM6 (CHAK2) (TRPM6 产品)
    别名
    TRPM6 antibody, CHAK2 antibody, HMGX antibody, HOMG antibody, HOMG1 antibody, HSH antibody, TRPM6/CHAK2 antibody, transient receptor potential cation channel subfamily M member 6 antibody, transient receptor potential cation channel, subfamily M, member 6 antibody, TRPM6 antibody, Trpm6 antibody
    背景
    CHAK2 is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. It is also upregulated in certain forms of cancer and could play a role in diabetes.
    分子量
    231708
    基因ID
    140803
    NCBI登录号
    NP_001170781, NP_001170782, NP_060132
    UniProt
    Q9BX84
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