IRAK1 抗体 (C-Term)
Quick Overview for IRAK1 抗体 (C-Term) (ABIN392233)
抗原
See all IRAK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 683-712, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This IRAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 683-712 amino acids from the C-terminal region of human IRAK.
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亚型
- Ig Fraction
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anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 301-400) antibody
IRAK1 适用: 人, 大鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 530-693) antibodyIRAK1 适用: 人 WB, ELISA, IF, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 530-693) antibodyIRAK1 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 3F7 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 530-693) antibodyIRAK1 适用: 人 WB, IF, IP, IHC (p), EIA 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (pThr209) antibodyIRAK1 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 348-381), (pSer376) antibodyIRAK1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB56575 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 424-633) antibodyIRAK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 683-712) antibodyIRAK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (pThr387) antibodyIRAK1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (pThr209) antibodyIRAK1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
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别名
- IRAK
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背景
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.
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分子量
- 76537
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基因ID
- 3654
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NCBI登录号
- NP_001020413, NP_001020414, NP_001560
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UniProt
- P51617
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途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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