RUNX2 抗体 (AA 445-474)
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Quick Overview for RUNX2 抗体 (AA 445-474) (ABIN392133)
抗原
See all RUNX2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 445-474
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This RUNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids surrounding S465 of human RUNX2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. IHC-P: 1:10~50. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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别名
- RUNX2
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背景
- Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
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分子量
- 56648
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基因ID
- 860
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NCBI登录号
- NP_001015051, NP_001019801
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UniProt
- Q13950
抗原
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