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MGMT 抗体 (C-Term)

Name: MGMT 抗体 (C-Term)
SKU: ABIN391514
Availability: OutOfStock

This anti-MGMT antibody is a 兔多克隆 antibody detecting MGMT in WB, FACS 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.

MGMT Antibody (C-term) (ABIN391514 and ABIN2841475) western blot analysis in Jurkat cell line lysates (35 μg/lane). (MGMT 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human placenta with MGMT Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (MGMT 抗体 (C-Term))

IHC (p)

Flow cytometric analysis of CEM cells using MGMT Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). (MGMT 抗体 (C-Term))

FACS

3 images

(2 references)

产品编号 ABIN391514

发货至: 中国

Quick Overview for MGMT 抗体 (C-Term) (ABIN391514)

抗原

See all MGMT 抗体

MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

适用

人

宿主

兔

克隆类型

多克隆

标记

This MGMT antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB19082

Discover our top product MGMT Primary Antibody

抗原表位
13

12

8

5

4

3

2

2

1

1

1

1

1

1

1

1

1
AA 156-182, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This MGMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-182 amino acids from the C-terminal region of human MGMT.

亚型

Ig Fraction
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 32-210) antibody
MGMT 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1A11F8 unconjugated

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 101-207) antibody
MGMT 适用: 大鼠 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibody
MGMT 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (N-Term) antibody
MGMT 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibody
MGMT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 156-182) antibody
MGMT 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) antibody
MGMT 适用: 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibody
MGMT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibody
MGMT 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) antibody
MGMT 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C12 unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Ge, Guo, Zhang, Lin, Li, Liu, Kong, Fang, Zhao: "Impact of O6-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinoma." in: Japanese journal of clinical oncology, (2015) (PubMed).

Wu, Cai, Lin, Xiong, Lu, Mao, Yao, Zhou: "High-mobility group box 2 is associated with prognosis of glioblastoma by promoting cell viability, invasion, and chemotherapeutic resistance." in: Neuro-oncology, Vol. 15, Issue 9, pp. 1264-75, (2013) (PubMed).
抗原

MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

别名

MGMT

背景

MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. This protein repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the protein is irreversibly inactivated.

分子量

21646

基因ID

4255

UniProt

P16455

途径

DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus