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BRSK2 抗体 (C-Term)

BRSK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5548 unconjugated
产品编号 ABIN391285
发货至: 中国
  • 抗原 See all BRSK2 抗体
    BRSK2 (BR serine/threonine Kinase 2 (BRSK2))
    抗原表位
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    AA 706-736, C-Term
    适用
    • 24
    • 20
    • 2
    宿主
    • 30
    • 2
    • 1
    克隆类型
    • 33
    多克隆
    标记
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BRSK2 antibody is un-conjugated
    应用范围
    • 24
    • 22
    • 7
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This STK29 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-736 amino acids from the C-terminal region of human STK29.
    克隆位点
    RB5548
    亚型
    Ig Fraction
    Top Product
    Discover our top product BRSK2 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    BRSK2 (BR serine/threonine Kinase 2 (BRSK2))
    别名
    STK29 (BRSK2 产品)
    别名
    C11orf7 antibody, PEN11B antibody, SAD1 antibody, SADA antibody, STK29 antibody, BRSK2 antibody, 4833424K13Rik antibody, SAD-A antibody, BR serine/threonine kinase 2 antibody, BRSK2 antibody, Brsk2 antibody
    背景
    BRSK2 expressed in insect cells specifically phosphorylates WEE1A, CDC25C, and CDC25B in an in vitro assay, but a kinase-dead mutant does not. Overexpression of BRSK2 in HeLa cells results in increased phosphorylation of CDC25C. DNA damage induced by ultraviolet (UV) irradiation or methyl methane sulfonate, but not by ionizing radiation, enhances endogenous BRSK2 kinase activity in a caffeine-sensitive manner and causes translocation of BRSK2 from the cytoplasm to the nucleus. Overexpression of BRSK2 induces G2/M arrest in HeLa cells. Small interfering RNA against BRSK2 partly abrogates UV-induced G2/M arrest. BRSK2 may act as a checkpoint kinase upon DNA damage induced by UV irradiation or methyl methane sulfonate.
    分子量
    81633
    基因ID
    9024
    NCBI登录号
    NP_001243556, NP_001243558, NP_001243559, NP_003948
    UniProt
    Q8IWQ3
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