This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SPINK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the N-terminal region of human SPINK5.
SPINK5 is a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The inhibitor may play a role in skin and hair morphogenesis and anti-inflammatory and/or antimicrobial protection of mucous epithelia. Mutations may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy.