TBP 抗体 (C-Term)
Quick Overview for TBP 抗体 (C-Term) (ABIN390630)
抗原
See all TBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 301-330, C-Term
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预测反应
- B, C, Pr, M, X
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This TBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-330 amino acids from the C-terminal region of human TBP.
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亚型
- Ig Fraction
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anti-TATA Box Binding Protein (TBP) (AA 1-144) antibody
TBP 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7G11C8 unconjugated
anti-TATA Box Binding Protein (TBP) (AA 210-239) antibodyTBP 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-TATA Box Binding Protein (TBP) antibodyTBP 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 830CT4-3-3 unconjugated
anti-TATA Box Binding Protein (TBP) (AA 301-330) antibodyTBP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TATA Box Binding Protein (TBP) (N-Term) antibodyTBP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TATA Box Binding Protein (TBP) (AA 39-50) antibodyVerified TBP 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-TATA Box Binding Protein (TBP) (AA 210-239) antibodyTBP 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB20259 unconjugated
anti-TATA Box Binding Protein (TBP) antibodyTBP 适用: 人, 小鼠, 大鼠, Cynomolgus WB, IHC (p), IF (cc) 宿主: 小鼠 Monoclonal 8C4 unconjugated
anti-TATA Box Binding Protein (TBP) (AA 8-316) antibodyTBP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TATA Box Binding Protein (TBP) (AA 1-55) antibodyTBP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- TBP (TATA Box Binding Protein (TBP))
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别名
- TBP
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背景
- Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
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分子量
- 37698
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基因ID
- 6908
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NCBI登录号
- NP_001165556, NP_003185
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UniProt
- P20226
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途径
- WNT signaling
抗原
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