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TDG 抗体 (C-Term)

This anti-TDG antibody is a 兔 多克隆 antibody detecting TDG in WB 和 FACS. Suitable for 人.
产品编号 ABIN390560
发货至: 中国

Quick Overview for TDG 抗体 (C-Term) (ABIN390560)

抗原

See all TDG 抗体
TDG (Thymine-DNA Glycosylase (TDG))

适用

  • 50
  • 19
  • 11
  • 2
  • 2

宿主

  • 38
  • 12

克隆类型

  • 41
  • 10
多克隆

标记

  • 44
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TDG antibody is un-conjugated

应用范围

  • 40
  • 14
  • 11
  • 11
  • 6
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB19894
  • 抗原表位

    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 281-310, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This TDG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the C-terminal region of human TDG.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    TDG (Thymine-DNA Glycosylase (TDG))

    别名

    TDG

    背景

    The protein TDG belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.

    分子量

    46053

    基因ID

    6996

    NCBI登录号

    NP_003202

    UniProt

    Q13569

    途径

    DNA Damage Repair, Chromatin Binding
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