Neuregulin 1 抗体 (AA 198-229)
(1 reference)Quick Overview for Neuregulin 1 抗体 (AA 198-229) (ABIN390160)
抗原
See all Neuregulin 1 (NRG1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 198-229
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This NRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-229 amino acids from the Central region of human NRG1.
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亚型
- Ig Fraction
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anti-Neuregulin 1 (NRG1) (AA 617-636), (C-Term) antibody
NRG1 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (C-Term) antibodyNRG1 适用: 人, 大鼠, 小鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (N-Term) antibodyNRG1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 198-229) antibodyNRG1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 221-320) antibodyNRG1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 1-241) antibodyNRG1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 21-242) antibodyNRG1 适用: 人 ELISA, IF, Coat 宿主: 小鼠 Monoclonal NRG1-2752 unconjugated
anti-Neuregulin 1 (NRG1) (AA 21-242) antibodyNRG1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal NRG1-2710 unconjugated
anti-Neuregulin 1 (NRG1) antibodyNRG1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (Isoform 10) antibodyNRG1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Deciphering the luteal transcriptome: potential mechanisms mediating stage-specific luteolytic response of the corpus luteum to prostaglandin F??." in: Physiological genomics, Vol. 43, Issue 8, pp. 447-56, (2011) (PubMed).
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: "Deciphering the luteal transcriptome: potential mechanisms mediating stage-specific luteolytic response of the corpus luteum to prostaglandin F??." in: Physiological genomics, Vol. 43, Issue 8, pp. 447-56, (2011) (PubMed).
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- Neuregulin 1 (NRG1)
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别名
- NRG1
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背景
- Neuregulin 1 (NRG1) was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specifically expressed and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains, and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.
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分子量
- 70392
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基因ID
- 3084
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NCBI登录号
- NP_001153467, NP_001153471, NP_001153473, NP_001153477, NP_001153480, NP_039250, NP_039251, NP_039252, NP_039253, NP_039254, NP_039256, NP_039258
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UniProt
- Q02297
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
抗原
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