MLLT6 抗体 (C-Term)
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- 抗原 See all MLLT6 products
- MLLT6 (Myeloid/lymphoid Or Mixed-lineage Leukemia, Translocated To, 6 (MLLT6))
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抗原表位
- AA 1056-1086, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MLLT6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This MLLT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1056-1086 amino acids from the C-terminal region of human MLLT6.
- 克隆位点
- RB2251-2252
- 亚型
- Ig Fraction
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anti-Myeloid/lymphoid Or Mixed-lineage Leukemia, Translocated To, 6 (MLLT6) (AA 1-462) antibody
MLLT6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-Myeloid/lymphoid Or Mixed-lineage Leukemia, Translocated To, 6 (MLLT6) antibodyMLLT6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-lineage Leukemia, Translocated To, 6 (MLLT6) (AA 1-325) antibodyMLLT6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- MLLT6 (Myeloid/lymphoid Or Mixed-lineage Leukemia, Translocated To, 6 (MLLT6))
- 别名
- MLLT6 (MLLT6 产品)
- 别名
- AF17 antibody, MLLT6, PHD finger containing antibody, MLLT6 antibody
- 背景
- Band 11q23 chromosome locations are associated with approximately 10 % of patients with acute lymphoblastic leukemia (ALL) and more than 5 % of patients with acute myeloid leukemia (AML). 11q23 translocation associated leukemias typically jointly express lymphoid and myeloid markers and exhibit poor prognosis. The gene at 11q23 involved in the translocations is known by multiple names, including ALL1, HRX, MLL, and TRX1. One of the more infrequent translocations, t(11,17)(q23,q21), MLLT6, encodes a protein of 1,093 amino acids, containing a leucine-zipper dimerization motif 3-prime to the fusion point and a cysteine-rich domain at the end terminus that can be arranged in 3 zinc fingers. MMLT6 contains amino acid runs associated with domains involved in transcriptional repression or activation. It has been proposed that MLLT6 represses truncated ALL1 function or inhibits function of the normal protein in leukemic cells.
- 分子量
- 112048
- 基因ID
- 4302
- NCBI登录号
- NP_005928
- UniProt
- P55198
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