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LRP3 抗体 (C-Term)

LRP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2239 unconjugated
产品编号 ABIN390097
发货至: 中国
  • 抗原 See all LRP3 抗体
    LRP3 (Low Density Lipoprotein Receptor-Related Protein 3 (LRP3))
    抗原表位
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 661-692, C-Term
    适用
    • 18
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 16
    • 2
    克隆类型
    • 16
    • 2
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LRP3 antibody is un-conjugated
    应用范围
    • 10
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This LRP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 661-692 amino acids from the C-terminal region of human LRP3.
    克隆位点
    RB2239
    亚型
    Ig Fraction
    Top Product
    Discover our top product LRP3 Primary Antibody
  • 应用备注
    WB: 1:2000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    LRP3 (Low Density Lipoprotein Receptor-Related Protein 3 (LRP3))
    别名
    LRP3 (LRP3 产品)
    别名
    LRP3 antibody, LDL receptor related protein 3 antibody, LDL receptor related protein 3 S homeolog antibody, low density lipoprotein receptor-related protein 3 antibody, LRP3 antibody, lrp3.S antibody, Lrp3 antibody
    背景
    Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration (1). Structurally, members of the LDLR family share homology within their extracellular domains, which are highlighted by the presence of clusters of ligand-binding repeats. LRP is a large endocytic receptor that participates in several biological pathways and plays prominent roles in lipoprotein metabolism and in the catabolism of proteinases involved in coagulation and fibrinolysis. LRP also mediates the cellular entry of certain viruses and toxins and facilitates the activation of various lysosomal enzymes (2). All LRPs are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment. The mechanisms by which they regulate the formation of the nervous system are varied and include the transduction of extracellular signals and the modulation of intracellular signal propagation, as well as cargo transport, the function most commonly attributed to this gene family (3).
    分子量
    82884
    基因ID
    4037
    NCBI登录号
    NP_002324
    UniProt
    O75074
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