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JNK 抗体 (pThr183)

This anti-JNK antibody is a 兔 多克隆 antibody detecting JNK in DB. Suitable for 人.
产品编号 ABIN389822
发货至: 中国
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北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for JNK 抗体 (pThr183) (ABIN389822)

抗原

See all JNK (MAPK8) 抗体
JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

适用

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宿主

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克隆类型

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多克隆

标记

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This JNK antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB13240
  • 抗原表位

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    pThr183

    预测反应

    M, Rat, X

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MAPK8 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T183 of human MAPK8.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

    别名

    MAPK8

    背景

    MAPK8 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.

    分子量

    48296

    基因ID

    5599

    NCBI登录号

    NP_001265476, NP_002741, NP_620634, NP_620637

    UniProt

    P45983

    途径

    MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
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