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FAS 抗体 (pTyr291)

This anti-FAS antibody is a 兔 多克隆 antibody detecting FAS in DB. Suitable for 人.
产品编号 ABIN389708
发货至: 中国

Quick Overview for FAS 抗体 (pTyr291) (ABIN389708)

抗原

See all FAS 抗体
FAS (TNF Receptor Superfamily, Member 6 (FAS))

适用

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宿主

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克隆类型

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多克隆

标记

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This FAS antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB11173
  • 抗原表位

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    pTyr291

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This FAS Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y291 of human FAS.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    FAS (TNF Receptor Superfamily, Member 6 (FAS))

    别名

    FAS

    背景

    FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells.

    分子量

    37732

    基因ID

    355

    NCBI登录号

    NP_000034, NP_690610, NP_690611

    UniProt

    P25445

    途径

    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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