PCNA 抗体 (C-Term)
Quick Overview for PCNA 抗体 (C-Term) (ABIN389344)
抗原
See all PCNA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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    - 
                                            抗原表位
- AA 231-261, C-Term
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                                            预测反应
- B, Ha, Pr, Rat
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                                            纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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                                            免疫原
- This PCNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-261 amino acids from the C-terminal region of human PCNA.
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                                            亚型
- Ig Fraction
 
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    - 
                                            应用备注
- IF: 1:10~50. IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:10~50
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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                                            有效期
- 6 months
 
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    - 
                                            : "DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells."    in: Journal of virology, Vol. 91, Issue 1, (2017)         (PubMed).        
 : "Liuweiwuling tablets attenuate acetaminophen-induced acute liver injury and promote liver regeneration in mice." in: World journal of gastroenterology : WJG, Vol. 21, Issue 26, pp. 8089-95, (2015) (PubMed).
 : "Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces ?-secretase (BACE1) levels and A? generation." in: The Journal of biological chemistry, Vol. 287, Issue 11, pp. 8424-33, (2012) (PubMed).
 : "DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5639-49, (2012) (PubMed).
 : "Lentiviral vector-mediated PAX6 overexpression promotes growth and inhibits apoptosis of human retinoblastoma cells." in: Investigative ophthalmology & visual science, Vol. 52, Issue 11, pp. 8393-400, (2011) (PubMed).
 
 
- 
                                            : "DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells."    in: Journal of virology, Vol. 91, Issue 1, (2017)         (PubMed).        
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    - PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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                                            别名
- PCNA
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                                            背景
- PCNA is found in the nucleus and is a cofactor of DNA polymerase delta. This protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.
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                                            分子量
- 28769
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                                            基因ID
- 5111
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                                            NCBI登录号
- NP_002583, NP_872590
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                                            UniProt
- P12004
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                                            途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
 抗原
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