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Ataxin 3 抗体 (N-Term)

This anti-Ataxin 3 antibody is a 兔 多克隆 antibody detecting Ataxin 3 in IHC (p). Suitable for 人.
产品编号 ABIN388975
发货至: 中国

Quick Overview for Ataxin 3 抗体 (N-Term) (ABIN388975)

抗原

See all Ataxin 3 (ATXN3) 抗体
Ataxin 3 (ATXN3)

适用

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宿主

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克隆类型

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多克隆

标记

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This Ataxin 3 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB4606
  • 抗原表位

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    AA 29-59, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This Ataxin3 (MJD) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-59 amino acids from the N-terminal region of human Ataxin3 (MJD).

    亚型

    Ig Fraction
  • 应用备注

    IHC-P: 1:50~100. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Ataxin 3 (ATXN3)

    别名

    Ataxin3 (MJD)

    背景

    Machado-Joseph disease is an autosomal dominant neurologic disorder, and is now known to be the same as previously described spinocerebellar ataxia-3. MJD protein (Ataxin-3) contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. This protein interacts with key regulators (CBP, p300 and PCAF) of transcription and represses transcription, and also acts as a histone-binding protein that regulates transcription. MJD is a deubiquitinating enzyme.

    分子量

    41250

    基因ID

    4287

    NCBI登录号

    NP_001121168, NP_001158252, NP_004984, NP_109376

    UniProt

    P54252
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