BID 抗体 (AA 68-103)
Quick Overview for BID 抗体 (AA 68-103) (ABIN388099)
抗原
See all BID 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 68-103
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This Bid antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-103 amino acids from human Bid.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2." in: Human molecular genetics, Vol. 19, Issue 15, pp. 2974-86, (2010) (PubMed).
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: "ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2." in: Human molecular genetics, Vol. 19, Issue 15, pp. 2974-86, (2010) (PubMed).
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- BID (BH3 Interacting Domain Death Agonist (BID))
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别名
- Bid
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背景
- Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release.
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分子量
- 21995
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基因ID
- 637
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NCBI登录号
- NP_001187, NP_001231496, NP_001231498, NP_001231499, NP_001231501, NP_932070, NP_932071
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UniProt
- P55957
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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