Cyclic GMP 抗体
cGMP
ELISA, WB
宿主: 小鼠
Monoclonal
2F11E10
unconjugated
1 image
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- 抗原 See all Cyclic GMP (cGMP) 抗体
- Cyclic GMP (cGMP)
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Cyclic GMP antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 特异性
- The specificity of the antibody is defined as the ratio of antigen concentration to cross-reactant concentration at 50% inhibition of maximum binding.
- 纯化方法
- Protein A affinity column
- 免疫原
- 3', 5'-cyclic GMP-8-KLH
- 克隆位点
- 2F11E10
- 亚型
- IgG1
- Top Product
- Discover our top product cGMP Primary Antibody
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anti-Cyclic GMP (cGMP) antibody
cGMP IF (p), IF (cc), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
- 缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium azide
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid repeated freezing and thawing cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
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- 抗原
- Cyclic GMP (cGMP)
- 别名
- cGMP (cGMP 产品)
- 物质类
- Chemical
- 背景
- CGMP acts as a secondary messenger much like cyclic AMP. It is generally known to activate intracellular protein kinases in response to the binding of membrane-impermeable peptide hormones to the cell surface. cGMP synthesis is catalyzed by guanylate cyclase (GC), which converts GTP to cGMP. Membrane-bound GC is activated by peptide hormones such as atrial natriuretic factor, while soluble GC is typically activated by nitric oxide (NO) to stimulate cGMP synthesis.cGMP is also a common regulator of ion channel conductance, glycogenolysis, and cellular apoptosis. It also relaxes smooth muscle tissues. The roles of cGMP and cAMP may be linked, as evidenced by the fact that some cellular functions are controlled bi-directionally by both cAMP and cGMP. Some functions are stimulated by cGMP and suppressed by cAMP and vice versa.
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