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P2RX4 抗体 (C-Term)

P2RX4 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN375223
发货至: 中国
  • 抗原 See all P2RX4 抗体
    P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))
    抗原表位
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 27
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬
    宿主
    • 25
    • 2
    • 2
    山羊
    克隆类型
    • 29
    多克隆
    标记
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P2RX4 antibody is un-conjugated
    应用范围
    • 19
    • 11
    • 6
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-YREKKYKYVE DYEQ
    特异性
    This antibody detects P2X4.
    交叉反应 (详细)
    Species reactivity (expected):Rat, Canine (Dog), Bovine.
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Affinity Chromatography
    免疫原
    Peptide with sequence from the C-Terminus of the protein sequence
    Top Product
    Discover our top product P2RX4 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Girón, Vílchez, Shreeram, Salto, Manzano, Cabrera, Campos, Edens, Rueda, López-Pedrosa: "β-Hydroxy-β-methylbutyrate (HMB) normalizes dexamethasone-induced autophagy-lysosomal pathway in skeletal muscle." in: PLoS ONE, Vol. 10, Issue 2, pp. e0117520, (2016) (PubMed).

    Millet, Martin, Bonnefoy, Saas, Mocek, Alkan, Terrier, Kerstein, Tamassia, Satyanarayanan, Ariel, Ribeil, Guillevin, Cassatella, Mueller, Thieblemont, Lamprecht, Mouthon, Perruche, Witko-Sarsat: "Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis." in: The Journal of clinical investigation, Vol. 125, Issue 11, pp. 4107-21, (2016) (PubMed).

    Moshfegh, Aires, Kisielow, Vogel: "A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways." in: Scientific reports, Vol. 6, pp. 25104, (2016) (PubMed).

    Nassar, Halle, Plagemann, Tzschentke et al.: "Detection of long-term influence of prenatal temperature stimulation on hypothalamic type-II iodothyronine deiodinase in juvenile female broiler chickens using a novel immunohistochemical ..." in: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 179, pp. 120-4, (2015) (PubMed).

    Ott, Plitzko, Krischkowski, Reichmann, Bittner, Mendel, Kunze, Clement, Havemeyer: "Reduction of sulfamethoxazole hydroxylamine (SMX-HA) by the mitochondrial amidoxime reducing component (mARC)." in: Chemical research in toxicology, Vol. 27, Issue 10, pp. 1687-95, (2015) (PubMed).

    Grill, Neumann, Hiltwein, Kolligs, Schneider: "Intestinal E-cadherin Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis." in: Digestive diseases and sciences, Vol. 60, Issue 4, pp. 895-902, (2015) (PubMed).

    Raz, Buijze, Raz, Verwey, Anvar, Aartsma-Rus, van der Maarel: "A novel feed-forward loop between ARIH2 E3-ligase and PABPN1 regulates aging-associated muscle degeneration." in: The American journal of pathology, Vol. 184, Issue 4, pp. 1119-31, (2014) (PubMed).

    Cruz-Orengo, Daniels, Dorsey, Basak, Grajales-Reyes, McCandless, Piccio, Schmidt, Cross, Crosby, Klein: "Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility." in: The Journal of clinical investigation, Vol. 124, Issue 6, pp. 2571-84, (2014) (PubMed).

    Morgan, Cheepala, Wang, Neale, Adachi, Nachagari, Leggas, Zhao, Boyd, Venkataramanan, Schuetz: "Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 14456-66, (2012) (PubMed).

    Freeman, Bowman, Zetter: "Regenerative protein thymosin beta-4 is a novel regulator of purinergic signaling." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 3, pp. 907-15, (2011) (PubMed).

    Chentoufi, Kritzer, Tran, Dasgupta, Lim, Yu, Afifi, Jiang, Carpenter, Osorio, Hsiang, Nesburn, Wechsler, BenMohamed: "The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism." in: Journal of virology, Vol. 85, Issue 17, pp. 9127-38, (2011) (PubMed).

    Surgucheva, Shestopalov, Surguchov: "Effect of gamma-synuclein silencing on apoptotic pathways in retinal ganglion cells." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36377-85, (2008) (PubMed).

    Niculescu, Perrine, Miller, Ehrlich, Unterwald: "Trk: a neuromodulator of age-specific behavioral and neurochemical responses to cocaine in mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 5, pp. 1198-207, (2008) (PubMed).

  • 抗原
    P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))
    别名
    P2RX4 / P2X4 (P2RX4 产品)
    别名
    P2X4 antibody, P2X4R antibody, AI504491 antibody, AW555605 antibody, D5Ertd444e antibody, p2rx4 antibody, p2x4 antibody, wu:fi03f02 antibody, p2x4r antibody, p2rx4.2 antibody, p2xr4.2 antibody, purinergic receptor P2X 4 antibody, purinergic receptor P2X, ligand-gated ion channel 4 antibody, purinergic receptor P2X, ligand-gated ion channel, 4a antibody, purinergic receptor P2X, ligand gated ion channel, 4 L homeolog antibody, purinergic receptor P2X, ligand-gated ion channel, 4b antibody, P2RX4 antibody, P2rx4 antibody, p2rx4a antibody, p2rx4.L antibody, p2rx4b antibody
    背景
    The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants have been identified for this gene although their full-length natures have not been determined. [provided by RefSeq]Synonyms: ATP receptor, P2X purinoceptor 4, Purinergic receptor
    分子量
    43.4 kDa (NP_002551.2)
    基因ID
    5025
    NCBI登录号
    NP_002551
    UniProt
    Q99571
    途径
    Synaptic Membrane
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