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ARNTL 抗体 (both Isoforms, Internal Region)

ARNTL 适用: 人, 大鼠, 小鼠, Cow, 犬, Pig WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN375102
发货至: 中国
  • 抗原 See all ARNTL 抗体
    ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))
    抗原表位
    • 16
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    both Isoforms, Internal Region
    适用
    • 63
    • 48
    • 46
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, Cow, 犬, Pig
    宿主
    • 60
    • 6
    • 1
    山羊
    克隆类型
    • 54
    • 13
    多克隆
    标记
    • 35
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARNTL antibody is un-conjugated
    应用范围
    • 49
    • 18
    • 16
    • 14
    • 13
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    特异性
    This antibody is expected to recognize both reported isoforms (NP_001025444.1, NP_001025443.1) of BMAL1
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Bovine, Canine, Pig.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide with sequence REKITTNCYKFKIKD, from the internal region of the protein sequence according to NP_001169.3, NP_001025444.1.
    Top Product
    Discover our top product ARNTL Primary Antibody
  • 应用备注
    Peptide ELISA: 1/8000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))
    别名
    ARNTL / BMAL1 (ARNTL 产品)
    别名
    BMAL1 antibody, BMAL1c antibody, JAP3 antibody, MOP3 antibody, PASD3 antibody, TIC antibody, bHLHe5 antibody, Bmal1 antibody, ARNTL antibody, xBmal1 antibody, arntl antibody, Arnt3 antibody, BMAL1b antibody, bmal1b' antibody, aryl hydrocarbon receptor nuclear translocator like antibody, aryl hydrocarbon receptor nuclear translocator-like antibody, aryl hydrocarbon receptor nuclear translocator like S homeolog antibody, ARNTL antibody, Arntl antibody, arntl.S antibody, arntl antibody
    背景
    BMAL1 is a putative transcription factor involved in the generation of biological rhythms. It activates cycling transcription of Period (PER) and Timeless (TIM) by binding to the E-box (3'-CACGTG-5') present in their promoters. BMAL1 gene cyc mutants don't display PER and TIM cycling, and are completely arrhythmic. Efficient DNA binding requires dimerization with another bHLH protein, BMAL1 forms a heterodimer with Clock in order to activate PER and TIM transcription.Synonyms: Aryl hydrocarbon receptor nuclear translocator-like protein 1, BHLHE5, Basic-helix-loop-helix-PAS protein MOP3, Brain and muscle ARNT-like 1, Class E basic helix-loop-helix protein 5, MOP3, Member of PAS protein 3, PAS domain-containing protein 3, PASD3, bHLH-PAS protein JAP3, bHLHe5
    基因ID
    406, 9606
    UniProt
    O00327
    途径
    Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect
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