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SULF2 抗体 (Internal Region)

SULF2 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN375090
发货至: 中国
  • 抗原 See all SULF2 抗体
    SULF2 (Sulfatase 2 (SULF2))
    抗原表位
    • 15
    • 9
    • 8
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 41
    • 19
    • 19
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 54
    • 3
    • 1
    山羊
    克隆类型
    • 55
    • 3
    多克隆
    标记
    • 18
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SULF2 antibody is un-conjugated
    应用范围
    • 45
    • 25
    • 13
    • 13
    • 11
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    特异性
    This antibody is expected to recognize both reported isoforms (NP_061325.1 and NP_940998.1).
    纯化方法
    Affinity Chromatography
    免疫原
    Peptide with sequence C-DGRVYHVGLGDAAQPR, from the internal region of the protein sequence
    Top Product
    Discover our top product SULF2 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/8000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide and 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SULF2 (Sulfatase 2 (SULF2))
    别名
    SULF2 (SULF2 产品)
    别名
    Sulf1 antibody, zgc:55612 antibody, SULF2 antibody, si:dkeyp-84g9.1 antibody, wu:fb48e04 antibody, HSULF-2 antibody, xtsulf2 antibody, 2010004N24Rik antibody, AU020235 antibody, MSulf-2 antibody, mKIAA1247 antibody, sulfatase 2a antibody, sulfatase 2 antibody, extracellular sulfatase Sulf-2 antibody, sulfatase 2b antibody, sulfatase 2 S homeolog antibody, sulf2a antibody, SULF2 antibody, LOC100540921 antibody, sulf2 antibody, sulf2b antibody, sulf2.S antibody, Sulf2 antibody
    背景
    Sulf-2 exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Mammalian Sulfs are endoproteolytically processed and secreted into the extracellular space of transfected cells, where they exhibit both arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity against intact heparin. Though the molecular weight of full length human Sulf2 is 100455 Da (870 amino acids), the endogenous Sulf2 is found by western blot to be present at molecular weights of 24.4, 33.7 and 51-60 kDa. Higher molecular weight species may be found depending on tissue and/or cell type. Analysis of human tumor tissue and tumor cell lines suggests that HSulf-1 is misregulated in cancers. HSulf-1 is found in a variety of normal tissues but is down-regulated in tumor cell lines originating from ovarian, breast, pancreatic, renal, and hepatocellular carcinoma. Tumors formed by cells expressing Sulf demonstrate enhanced extracellular matrix deposition. The 6-O-sulfation of heparan sulfate of myeloma tumor cells may be a critical factor in determiningand regulating the in vivo growth of this cancer.Synonyms: Extracellular sulfatase Sulf-2, KIAA1247
    基因ID
    55959, 9606
    UniProt
    Q8IWU5
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